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AXJ NEW YORK

Matt: Cancer Founder Mode

Posted on January 21, 2026

Sid Sijbrandi, a friend and a former CEO of Gitlab, has started to share some of the story of his journey with cancer.

Manager mode assumes that existing systems will surface the best options. When I was first diagnosed with cancer in 2022, I delegated the crucial analyses and decisions about my care to others. In late 2024, when my cancer reappeared and my doctors told me I had exhausted the standard of care and there were no trials for my situation, I realized that assumption might, quite literally, kill me. Founder Mode was my only option.

Founder Mode meant going deep on every diagnostic and treatment option. It meant assembling a team of physicians and scientists to work from first principles to understand what was possible beyond standard protocols. Together, we paved new roads to access the very cutting edge of science and technology. Today, thanks to the efforts of many people around the world and the support of my wife Karen, I currently have no evidence of disease.

Sid was already very inspiring before this journey, and this is especially impressive. Elliot Hershberg has the full story and analysis, including some predictions for the future of cancer treatment.

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